Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/3892
Título: The effect of long-chain polyunsaturated fatty acids intake during pregnancy on adiposity of healthy full-term offspring at birth
Autor: Pereira-da-Silva, Luís
Cabo, C.
Moreira, Ana Catarina
Papoila, A. L.
Virella, Daniel
Neves, R.
Palavras-chave: Pregnancy
Long-chain polyunsaturated fatty acids
LCPUFA
Adiposity
Body composition
Data: Mar-2015
Editora: Nature
Citação: Pereira-da-Silva L, Cabo C, Moreira AC, Papoila AL, Virella D, Neves R. The effect of long-chain polyunsaturated fatty acids intake during pregnancy on adiposity of healthy full-term offspring at birth. J Perinatol. 2015;35(3):177-80.
Resumo: Objective - The adjusted effect of long-chain polyunsaturated fatty acid (LCPUFA) intake during pregnancy on adiposity at birth of healthy full-term appropriate-for-gestational age neonates was evaluated. Study Design - In a cross-sectional convenience sample of 100 mother and infant dyads, LCPUFA intake during pregnancy was assessed by food frequency questionnaire with nutrient intake calculated using Food Processor Plus. Linear regression models for neonatal body composition measurements, assessed by air displacement plethysmography and anthropometry, were adjusted for maternal LCPUFA intakes, energy and macronutrient intakes, prepregnancy body mass index and gestational weight gain. Result - Positive associations between maternal docosahexaenoic acid intake and ponderal index in male offspring (β=0.165; 95% confidence interval (CI): 0.031–0.299; P=0.017), and between n-6:n-3 LCPUFA ratio intake and fat mass (β=0.021; 95% CI: 0.002–0.041; P=0.034) and percentage of fat mass (β=0.636; 95% CI: 0.125–1.147; P=0.016) in female offspring were found. Conclusion - Using a reliable validated method to assess body composition, adjusted positive associations between maternal docosahexaenoic acid intake and birth size in male offspring and between n-6:n-3 LCPUFA ratio intake and adiposity in female offspring were found, suggesting that maternal LCPUFA intake strongly influences fetal body composition.
Peer review: yes
URI: http://hdl.handle.net/10400.21/3892
DOI: 10.1038/jp.2014.188
Versão do Editor: http://www.nature.com/jp/journal/vaop/ncurrent/full/jp2014188a.html
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