Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/3393
Título: Osmolality of preterm formulas suplemented with monprotein energy supplements
Autor: Pereira-da-Silva, Luís
Dias, M. Pitta-Grós
Virella, D.
Moreira, Ana Catarina
Serelha, M.
Palavras-chave: Bronchopulmonary dysplasia
Energy supplements
Glucose polymers
Medium-chain triglycerides
Osmolality
Preterm formulas
Dietary proteins
Energy intake
Food, Fortified
Glucans
Infant, Newborn
Osmolar concentration
Triglycerides
Data: Fev-2008
Editora: Nature Publishing Group
Citação: Pereira-da-Silva L, Dias MP, Virella D, Moreira AC, Serelha M. Osmolality of preterm formulas suplemented with monprotein energy supplements. Eur J Clin Nutr. 2008;62(2):274-8.
Resumo: Background: Addition of energy supplements to preterm formulas is an optional strategy to increase the energy intake in infants requiring fluid restriction, in conditions like bronchopulmonary dysplasia. This strategy may lead to an undesirable increase in osmolality of feeds, the maximum recommended safe limit being 400 mOsm/kg. The aim of the study was to measure the changes in osmolality of several commercialized preterm formulas after addition of glucose polymers and medium-chain triglycerides. Methods: Osmolality was measured by the freezing point depression method. Six powdered formulas with concentrations of 14 g/100 ml and 16 g/100 ml, and five ready-to-feed liquid formulas were analyzed. All formulas, were supplemented with 10% (low supplementation) or 20% (high supplementation) of additional calories, respectively, in the form of glucose polymers and medium chain triglycerides, maintaining a 1:1 glucose:lipid calorie ratio. Inter-analysis and intra-analysis coefficients of variation of the measurements were always < 3.9%. Results: The mean osmolality (mOsm/kg) of the non-supplemented formulas varied between 268.5 and 315.3 mOsm/kg, increasing by 3–5% in low supplemented formulas, and by 6–10% in high supplemented formulas. None of the formulas analyzed exceeded 352.8 mOsm/kg. Conclusion: The supplementation of preterm formulas with nonprotein energy supplements with up to 20% additional calories did not exceed the maximum recommended osmolality for neonatal feedings.
Peer review: yes
URI: http://hdl.handle.net/10400.21/3393
Versão do Editor: http://www.nature.com/ejcn/journal/v62/n2/full/1602736a.html
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