Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/2514
Título: Analysis of the interference of endogenous circadian rhythms on 3'- deoxy- 3'- [18F]Fluorothymidine physiological uptake at the human bone marrow
Autor: Varela, N. M.
Lucena, Filipa
Carapinha, Maria João
Vieira, Lina
Palavras-chave: Nuclear medicine
Endogenous circadian rhythms
Human bone marrow
18F-Fluorothymidine
Data: Out-2011
Editora: Springer
Citação: Varela NM, Lucena F, Carapinha MJ, Vieira L. Analysis of the interference of endogenous circadian rhythms on 3'- deoxy- 3'- [18F]Fluorothymidine physiological uptake at the human bone marrow. Eur j Nucl Med Mol Imaging. 2011;38(2 Suppl):S452.
Resumo: The main purpose of the present study is to determine if the circadian rhythms present in the human bone marrow are likely to influence 3’- deoxy- 3’-[18F] Fluorothymidine (18F-FLT) uptake in the same organ. The 18F-FLT is a Thymidine analogous proliferation agent. The relatively high physiological uptake of this tracer in the bone marrow diminishes the Tumor/Background (T/B) ratio, decreasing the detection accuracy of PET/CT and possibly affecting SUV quantifications.
Peer review: yes
URI: http://hdl.handle.net/10400.21/2514
ISSN: 1619-7089
Versão do Editor: http://link.springer.com/content/pdf/10.1007%2Fs00259-011-1913-y.pdf
Aparece nas colecções:ESTeSL - Posters

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