Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/2347
Título: Role of malnutrition and parasite infections in the spatial variation in children’s anaemia risk in Northern Angola
Autor: Magalhães, Ricardo J.
Langa, António
Pedro, João Mário
Sousa-Figueiredo, J. C.
Clements, A. C.
Nery, S. V.
Palavras-chave: Tropical medicine
Malnutrition
Parasite infection
Risk factor
Malaria
Anaemia
Angola
Data: Nov-2012
Citação: Magalhães RJ, Langa A, Pedro JM, Sousa-Figueiredo JC, Clements AC, Nery SV. Role of malnutrition and parasite infections in the spatial variation in children’s anaemia risk in Northern Angola. In ASTMH 61th Annual Meeting, Atlanta (USA), November 11-15, 2012. Poster.
Resumo: Anaemia has a significant impact on child development and mortality and is a severe public health problem in most countries in sub-Saharan Africa. Nutritional and infectious causes of anaemia are geographically variable and anaemia maps based on information on the major aetiologies of anaemia are important for identifying communities most in need and the relative contribution of major causes. We investigated the consistency between ecological and individual-level approaches to anaemia mapping, by building spatial anaemia models for children aged ≤15 years using different modeling approaches. We aimed to a) quantify the role of malnutrition, malaria, Schistosoma haematobium and soil-transmitted helminths (STH) for anaemia endemicity in children aged ≤15 years and b) develop a high resolution predictive risk map of anaemia for the municipality of Dande in Northern Angola. We used parasitological survey data on children aged ≤15 years to build Bayesian geostatistical models of malaria (PfPR≤15), S. haematobium, Ascaris lumbricoides and Trichuris trichiura and predict small-scale spatial variation in these infections. The predictions and their associated uncertainty were used as inputs for a model of anemia prevalence to predict small-scale spatial variation of anaemia. Stunting, PfPR≤15, and S. haematobium infections were significantly associated with anaemia risk. An estimated 12.5%, 15.6%, and 9.8%, of anaemia cases could be averted by treating malnutrition, malaria, S. haematobium, respectively. Spatial clusters of high risk of anaemia (>86%) were identified. Using an individual-level approach to anaemia mapping at a small spatial scale, we found that anaemia in children aged ≤15 years is highly heterogeneous and that malnutrition and parasitic infections are important contributors to the spatial variation in anemia risk. The results presented in this study can help inform the integration of the current provincial malaria control program with ancillary micronutrient supplementation and control of neglected tropical diseases, such as urogenital schistosomiasis and STH infection.
Peer review: yes
URI: http://hdl.handle.net/10400.21/2347
Versão do Editor: http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=5a7d5c95-fe21-4ba4-af83-baff84067a08&cKey=f48ee013-f93c-4764-8589-856fe9280c92&mKey=%7bC0DC51D1-29D3-44C6-BC0E-2069047A3801%7d
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