Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/1928
Título: Biological monitoring of aflatoxin (AFB1) in workers of swine and poultry production
Autor: Viegas, Susana
Veiga, Luísa
Almeida, Ana
Figueiredo, Paula
Carolino, Elisabete
Viegas, Carla
Palavras-chave: Saúde ambiental
Saúde ocupacional
Aflatoxinas
Aviário
Environmental health
Occupational health
Aflatoxin B1
Poultry
Biological monitoring
Swine production
Data: Jun-2012
Editora: Elsevier
Citação: Viegas S, Veiga L, Almeida A, Figueiredo P, Carolino E, Viegas C. Biological monitoring of aflatoxin (AFB1) in workers of swine and poultry production. Toxicol Lett. 2012;211 Suppl:S49.
Resumo: Although a great body of literature exists concerning the ingestion of food contaminated with aflatoxin, there are still few studies regarding mycotoxin inhalation in occupational settings. Since mycotoxins are relatively non-volatile, inhalation exposure is cause by inhalation of airborne fungal particulates or fungi-contaminated substrates that contain aflatoxin. We intend to know if there is occupational exposure to aflatoxin in Portuguese poultry and swine production. A total of 19 individuals (11 swine; 8 poultry) agreed and provided blood samples during the course of this investigation. Measurement of AFB1 was performed by ELISA. The samples were treated with pronase (Merck), wash in a Column C18 and purification was made with immunoaffinity columns (R.biopharma), specific for AFB1. It was applied statistical test (Mann-Whitney) to verified statistical difference in AFB1 results between the two settings. Results varied with concentrations from <LOD to 5.96 ng ml-1 (Poultry: <LOD – 3.67 ng ml-1; Swine: <LOD -5.96 ng ml-1. There wasn’t found statistical difference between the two occupational settings, however, results reveal a tendency for poultry workers have higher aflatoxin values, probably because poultry activities are promoter of particles exposure. Only women’s in both settings have results <LOD. These results are probably due to differences in the activities performed. Exposure to air and dust containing aflatoxin by inhalation should be consider a route of exposure in both settings.
Peer review: yes
URI: http://hdl.handle.net/10400.21/1928
ISSN: 0378-4274
Versão do Editor: http://www.sciencedirect.com/science/article/pii/S0378427412003001
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